P63-α (3F11) Mouse mAb from ELK Biotechnology Read more ›
P63-α (3F11) Mouse mAb is a research-use antibody from ELK Biotechnology for studying P63-α (3F11) in WB, IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .
| Validation evidence captions | Western blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α（EM1404）Mouse mAb diluted at 1:2000. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1404 |
| Target | P63-α (3F11) |
| Research areas | Antibody Research |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,IHC |
| Conjugation | Unconjugated |
| Dilution range | WB 1:1,000-2,000 IHC:1;100-1:200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
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Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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