Primary Antibody ISO 9001|ABMIUM Verified™
ABM92608

P63-α (3F11) Mouse mAb

ISO 9001|ABMIUM Verified™|Antibody

P63-α (3F11) Mouse mAb from ELK Biotechnology Read more ›

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P63-α (3F11) Mouse mAb
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P63-α (3F11) Mouse mAb

Product Description

P63-α (3F11) Mouse mAb is an ELK Biotechnology antibody for research workflows involving P63-α (3F11).

Background

p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .

Additional antibody information

Validation evidence captions Western blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α(EM1404)Mouse mAb diluted at 1:2000. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α(EM1404)Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α(EM1404)Mouse mAb diluted at 1:200.

Key Facts

Product type Primary Antibody Target: P63-α (3F11)
Target P63-α (3F11)
Concentration 1mg/mL
Working concentration WB 1:1,000-2,000 IHC:1;100-1:200
Species reactivity Human, Rat, Mouse
Observed band 50-80kDa
Cellular localization Nucleus
Form / buffer Antibody solution
Research area Antibody Research
Host species Mouse
Clonality Monoclonal
Isotype IgG1
Conjugation Unconjugated
Tested applications
WBIHC
Dilution range WB 1:1,000-2,000 IHC:1;100-1:200
Immunogen Synthetic Peptide
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Reactivity & Application Validation

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMCHIP
Human
Rat
Mouse
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:1
Rat
Mouse
ABMIUM Validated™ IHC
Species Dilution Notes

Specifications

Target
P63-α (3F11)
Concentration
1mg/mL
Working concentration
WB 1:1,000-2,000 IHC:1;100-1:200
Form / buffer
Antibody solution
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human, Rat, Mouse
Tested applications
WBIHC
Immunogen
Synthetic Peptide
Observed band
50-80kDa
Cellular localization
Nucleus
Dilution range
WB 1:1,000-2,000 IHC:1;100-1:200

Storage & Stability

Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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