COX-2 (2G1) Mouse mAb from ELK Biotechnology Read more ›
COX-2 (2G1) Mouse mAb is a research-use antibody from ELK Biotechnology for studying COX-2 (2G1) in IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using COX-2（EM1339）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Ovarain Carcinoma Tissue using COX-2（EM1339）Mouse mAb diluted at 1:200. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1339 |
| Target | COX-2 (2G1) |
| Research areas | Antibody Research |
| Reactivity | Human,Mouse,Rat |
| Applications | IHC |
| Conjugation | Unconjugated |
| Dilution range | IHC 1:100-200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
| Mouse | — | — |
| Rat | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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