phospho-MLKL (S358) (6B4) Mouse mAb from ELK Biotechnology Read more ›
phospho-MLKL (S358) (6B4) Mouse mAb is a research-use antibody from ELK Biotechnology for studying phospho-MLKL (S358) (6B4) in IHC workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-MLKL S358（EM1320）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Phospho-MLKL S358（EM1320）Mouse mAb diluted at 1:200. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1320 |
| Target | phospho-MLKL (S358) (6B4) |
| Research areas | Antibody Research |
| Reactivity | Human |
| Applications | IHC |
| Conjugation | Unconjugated |
| Dilution range | IHC 1:100-200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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