Cystatin C (7F11) Mouse mAb from ELK Biotechnology Read more ›
Cystatin C (7F11) Mouse mAb is a research-use antibody from ELK Biotechnology for studying Cystatin C (7F11) in WB, IHC, ELISA workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1275 |
| Target | Cystatin C (7F11) |
| Research areas | Antibody Research |
| Reactivity | Human |
| Applications | WB,IHC,ELISA |
| Conjugation | Unconjugated |
| Dilution range | WB 1:1,000-2,000 IHC 1:100-200 ELISA 1:10,000-20,000 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Recombinant Protein |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Species | Dilution | Notes |
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| Species | Dilution | Notes |
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Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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