Cystatin C (7F11) Mouse mAb
Cystatin C (7F11) Mouse mAb from ELK Biotechnology Read more ›
Product Description
Cystatin C (7F11) Mouse mAb is an ELK Biotechnology antibody for research workflows involving Cystatin C (7F11).
Background
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200. |
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Key Facts
| Target | Cystatin C (7F11) |
| Also known as | AD8, Cystatin3, Gamma trace, HCCAA |
| Concentration | 1mg/mL |
| Working concentration | WB 1:1,000-2,000 IHC 1:100-200 ELISA 1:10,000-20,000 |
| Species reactivity | Human |
| Observed band | 14kDa |
| Cellular localization | Secreted |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WBIHCELISA |
| Dilution range | WB 1:1,000-2,000 IHC 1:100-200 ELISA 1:10,000-20,000 |
| Immunogen | Recombinant Protein |
Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Species | Dilution | Notes |
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| Species | Dilution | Notes |
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Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.