CD68 Mouse mAb
CD68 Mouse mAb from ELK Biotechnology Read more ›
Product Description
CD68 Mouse mAb is an ELK Biotechnology antibody for research workflows involving CD68.
Background
The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using CD68 （EM1162）Mouse mAb diluted at 1:500. |
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Key Facts
| Target | CD68 |
| Also known as | CD68 molecule, GP110, Macrosialin, SCARD1 |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:200-500 |
| Species reactivity | Human, Rat, Mouse |
| Cellular localization | Cell membrane and Endosome membrane. Lysosome membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:200-500 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200-500 | — |
| Rat | — | — |
| Mouse | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.