ABM92441
IDE/Insulin Degrading Enzyme Mouse mAb
ISO 9001|ABMIUM Verified™|Antibody
IDE/Insulin Degrading Enzyme Mouse mAb from ELK Biotechnology Read more ›
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Product Description
IDE/Insulin Degrading Enzyme Mouse mAb is an ELK Biotechnology antibody for research workflows involving IDE/Insulin Degrading Enzyme.
Background
Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
Additional antibody information
| Validation evidence captions | Western blot analysis of 1) Hela, 2) HepG2,with IDE Mouse mAb diluted at 1:2,000. | Western blot analysis of Hela, HepG2,with IDE Mouse mAb diluted at 1:2,000. |
|---|
Key Facts
Product type
Primary Antibody›
Target: IDE/Insulin Degrading Enzyme
| Target | IDE/Insulin Degrading Enzyme |
| Also known as | Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN |
| Concentration | 1mg/mL |
| Working concentration | WB 1:1,000 IHC 1:200 |
| Species reactivity | Human |
| Observed band | 118kDa |
| Cellular localization | Cell membrane, Cytoplasm, Membrane, Secreted |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WBIHC |
| Dilution range | WB 1:1,000 IHC 1:200 |
| Immunogen | Synthetic Peptide |
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Citations
ISO 9001
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Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
ABMIUM Validated™
WB
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
ABMIUM Validated™
IHC
| Species | Dilution | Notes |
|---|
Specifications
Target
IDE/Insulin Degrading Enzyme
Also known as
Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
Concentration
1mg/mL
Working concentration
WB 1:1,000 IHC 1:200
Form / buffer
Antibody solution
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human
Tested applications
WBIHC
Immunogen
Synthetic Peptide
Observed band
118kDa
Cellular localization
Cell membrane, Cytoplasm, Membrane, Secreted
Dilution range
WB 1:1,000 IHC 1:200
Storage & Stability
Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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