ABM92437
ErbB-2/HER-2 Mouse mAb
ISO 9001|ABMIUM Verified™|Antibody
ErbB-2/HER-2 Mouse mAb from ELK Biotechnology Read more ›
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Product Description
ErbB-2/HER-2 Mouse mAb is an ELK Biotechnology antibody for research workflows involving ErbB-2/HER-2.
Background
ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
Additional antibody information
| Validation evidence captions | Western blot analysis of 1) Hela, 2) 293, 3) Jurkat,with ErbB-2 Mouse mAb diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Human Breast Caricnoma using ErbB-2/HER-2（EM1079）Mouse mAb diluted at 1:500. |
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Key Facts
Product type
Primary Antibody›
Target: ErbB-2/HER-2
| Target | ErbB-2/HER-2 |
| Also known as | CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:1,000 IHC 1:200-500 |
| Species reactivity | Human |
| Observed band | 138kDa |
| Cellular localization | Cytoplasm. Nucleus and Cell membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WBIHC |
| Dilution range | WB 1:1,000 IHC 1:200-500 |
| Immunogen | Synthetic Peptide |
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Citations
ISO 9001
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Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
ABMIUM Validated™
WB
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
ABMIUM Validated™
IHC
| Species | Dilution | Notes |
|---|
Specifications
Target
ErbB-2/HER-2
Also known as
CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1
Concentration
1mg/mL
Working concentration
WB 1:1,000 IHC 1:200-500
Form / buffer
Antibody solution
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human
Tested applications
WBIHC
Immunogen
Synthetic Peptide
Observed band
138kDa
Cellular localization
Cytoplasm. Nucleus and Cell membrane
Dilution range
WB 1:1,000 IHC 1:200-500
Storage & Stability
Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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