GFAP Mouse mAb from ELK Biotechnology Read more ›
GFAP Mouse mAb is a research-use antibody from ELK Biotechnology for studying GFAP in WB, IHC workflows with listed reactivity for Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
| Validation evidence captions | Western blot analysis of Rat Brain Tissue with GFAP mAb diluted at 1:5,000. | Western blot analysis of Mouse Brain Tissue with GFAP mAb diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using GFAP(EM1059)Mouse mAb diluted at 1:500. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1059 |
| Target | GFAP |
| Research areas | Antibody Research |
| Reactivity | Rat,Mouse |
| Applications | WB,IHC |
| Conjugation | Unconjugated |
| Dilution range | WB 1:2,000-5,000 IHC 1:200-500 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Rat | WB 1:2 | — |
| Mouse | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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