CDX2 Mouse mAb
CDX2 Mouse mAb from ELK Biotechnology Read more ›
Product Description
CDX2 Mouse mAb is an ELK Biotechnology antibody for research workflows involving CDX2.
Background
CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.
Additional antibody information
| Validation evidence captions | Western blot analysis of 1) 293T, 2)Mouse Heart tissue with CDX2 mAb diluted at 1:2,000. | IHC staining of human rectal cancer tissue with CDX2 mouse mAb(14H6) diluted at 1:200. |
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Key Facts
| Target | CDX2 |
| Also known as | Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:1,000 IHC 1:200 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 42kDa |
| Cellular localization | Nucleus |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WBIHC |
| Dilution range | WB 1:1,000 IHC 1:200 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.