CD45 Mouse mAb from ELK Biotechnology Read more ›
CD45 Mouse mAb is a research-use antibody from ELK Biotechnology for studying CD45 in WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.
| Validation evidence captions | Western blot analysis of Hela with CD45 mAb diluted at 1:2,000. |
|---|
| Collaborator | ELK Biotechnology |
| Partner model | EM1046 |
| Target | CD45 |
| Research areas | Antibody Research |
| Reactivity | Human |
| Applications | WB |
| Conjugation | Unconjugated |
| Dilution range | WB 1:2,000 IHC 1:200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:2 | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
No customer reviews yet.
