CD45 Mouse mAb
CD45 Mouse mAb from ELK Biotechnology Read more ›
Product Description
CD45 Mouse mAb is an ELK Biotechnology antibody for research workflows involving CD45.
Background
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.
Additional antibody information
| Validation evidence captions | Western blot analysis of Hela with CD45 mAb diluted at 1:2,000. |
|---|
Key Facts
| Target | CD45 |
| Also known as | B220, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:2,000 IHC 1:200 |
| Species reactivity | Human |
| Observed band | 147kDa |
| Cellular localization | Membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WB |
| Dilution range | WB 1:2,000 IHC 1:200 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:2 | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.