Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM92404

ErbB-2/HER-2 Mouse mAb

ISO 9001|ABMIUM Verified™|Antibody

ErbB-2/HER-2 Mouse mAb from ELK Biotechnology Read more ›

ErbB-2/HER-2 Mouse mAb
Zoom
ErbB-2/HER-2 Mouse mAb

Product Description

ErbB-2/HER-2 Mouse mAb is a research-use antibody from ELK Biotechnology for studying ErbB-2/HER-2 in WB, IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.

Additional antibody information

Validation evidence captions Western blot analysis of 1) Hela, 2)Mouse Brain with ErbB-2/HER-2 mAb diluted at 1:4,000. | IHC staining of human breast cancer tissue with ErbB-2/HER-2 mouse mAb(11H9) diluted at 1:200.

Key Facts

Product typePrimary Antibody Target: ErbB-2/HER-2
Collaborator ELK Biotechnology
Partner model EM1045
Target ErbB-2/HER-2
Research areasAntibody Research
Reactivity Human,Rat,Mouse
Applications WB,IHC
ConjugationUnconjugated
Dilution rangeWB 1:2,000-4,000 IHC 1:200
Host Mouse
Clonality Monoclonal
Isotype IgG1
Immunogen Synthetic Peptide
Concentration 1mg/mL
Assay type Antibody validation/application
Why ABMIUM?
2,000+ Researchers trust us
50,000+ Citations
ISO 9001 Certified Collaborators
Independently handpicked Products selected for quality and fit

Application Validation Matrix

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMChIP
Human
Rat
Mouse
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:2
Rat
Mouse
ABMIUM Validated™ IHC
Species Dilution Notes

Specifications

Target
ErbB-2/HER-2
Also known as
CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1
Concentration
1mg/mL
Working concentration
WB 1:2,000-4,000 IHC 1:200
Form / buffer
Liquid
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human,Rat,Mouse
Tested applications
WBIHC
Immunogen
Synthetic Peptide
Observed band
138kDa
Cellular localization
Cytoplasm. Nucleus and Cell membrane
Dilution range
WB 1:2,000-4,000 IHC 1:200

Storage & Stability

Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

Customer Reviews

No customer reviews yet.