Galectin-3 Mouse mAb
Galectin-3 Mouse mAb from ELK Biotechnology Read more ›
Product Description
Galectin-3 Mouse mAb is an ELK Biotechnology antibody for research workflows involving Galectin-3.
Background
Galectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.
Additional antibody information
| Validation evidence captions | Western blot analysis of Hela, with Galectin-3 mAb diluted at 1:3,000. | IHC staining of Human thyroid tissue paraffin-embedded with Galectin-3 mouse mAb（6G2）diluted at 1:200. |
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Key Facts
| Target | Galectin-3 |
| Also known as | 35 kDa lectin, CBP 35, CBP35, Gal 3, GAL3, Galactose specific lectin 3, Galactoside binding protein, GALBP, Galectin 3, Galectin-3, GALIG, IgE binding protein, L 31, Laminin binding protein, Lectin L 29, LGALS2, LGALS3, Mac 2 antigen, MAC2 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:2,000 IHC 1:200 |
| Species reactivity | Human |
| Observed band | 26kDa |
| Cellular localization | Nucleus. Cytoplasmic in adenomas and carcinomas |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WBIHC |
| Dilution range | WB 1:2,000 IHC 1:200 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:2 | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.