ABM92400
Bcl-2 Mouse mAb
ISO 9001|ABMIUM Verified™|Antibody
Bcl-2 Mouse mAb from ELK Biotechnology Read more ›
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Product Description
Bcl-2 Mouse mAb is an ELK Biotechnology antibody for research workflows involving Bcl-2.
Background
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
Additional antibody information
| Validation evidence captions | Western blot analysis of Hela with Bcl-2 mouse mAb(6B5) diluted at 1:1,000. | IHC staining of Human tonsil tissue paraffin-embedded with Bcl-2 mouse mAb（6B5）diluted at 1:200. | Western blot analysis of 3T3 with Bcl-2 mouse mAb(6B5) diluted at 1:1,000. | IF analysis of Hela with EM1041(Left) and DAPI (Right) diluted at 1:100. |
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Key Facts
Product type
Primary Antibody›
Target: Bcl-2
| Target | Bcl-2 |
| Also known as | B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:1,000-2,000 IHC 1:200 IF 1:100-200 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 26kDa |
| Cellular localization | Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
WBIHCIF |
| Dilution range | WB 1:1,000-2,000 IHC 1:200 IF 1:100-200 |
| Immunogen | Synthetic Peptide |
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Citations
ISO 9001
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Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
ABMIUM Validated™
WB
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Rat | — | — |
| Mouse | — | — |
ABMIUM Validated™
IHC
| Species | Dilution | Notes |
|---|
ABMIUM Validated™
IF
| Species | Dilution | Notes |
|---|
Specifications
Target
Bcl-2
Also known as
B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2
Concentration
1mg/mL
Working concentration
WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
Form / buffer
Antibody solution
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human, Rat, Mouse
Tested applications
WBIHCIF
Immunogen
Synthetic Peptide
Observed band
26kDa
Cellular localization
Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
Dilution range
WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
Storage & Stability
Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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