Bcl-2 Mouse mAb from ELK Biotechnology Read more ›
Bcl-2 Mouse mAb is a research-use antibody from ELK Biotechnology for studying Bcl-2 in WB, IHC, IF workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
| Validation evidence captions | Western blot analysis of Hela with Bcl-2 mouse mAb(6B5) diluted at 1:1,000. | IHC staining of Human tonsil tissue paraffin-embedded with Bcl-2 mouse mAb（6B5）diluted at 1:200. | Western blot analysis of 3T3 with Bcl-2 mouse mAb(6B5) diluted at 1:1,000. | IF analysis of Hela with EM1041(Left) and DAPI (Right) diluted at 1:100. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1041 |
| Target | Bcl-2 |
| Research areas | Antibody Research |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,IHC,IF |
| Conjugation | Unconjugated |
| Dilution range | WB 1:1,000-2,000 IHC 1:200 IF 1:100-200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
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| Species | Dilution | Notes |
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Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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