CD10 Rabbit pAb
CD10 Rabbit pAb from ELK Biotechnology Read more ›
Product Description
CD10 Rabbit pAb is an ELK Biotechnology antibody for research workflows involving CD10.
Background
CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using CD10（EA321）Rabbit pAb diluted at 1:500. |
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Key Facts
| Target | CD10 |
| Also known as | CALLA, Enkephalinase,MME,NEP, Neutral endopeptidase antibody |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:200-500 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 85kDa |
| Cellular localization | Cell membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:200-500 |
| Immunogen | Recombinant Protein |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200-500 | — |
| Rat | — | — |
| Mouse | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.