CD10 Rabbit pAb from ELK Biotechnology Read more ›
CD10 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying CD10 in IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using CD10(EA321)Rabbit pAb diluted at 1:500. |
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| Collaborator | ELK Biotechnology |
| Partner model | EA321 |
| Target | CD10 |
| Research areas | Antibody Research |
| Reactivity | Human,Rat,Mouse |
| Applications | IHC |
| Conjugation | Unconjugated |
| Dilution range | IHC 1:200-500 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200-500 | — |
| Rat | — | — |
| Mouse | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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