VEGF Rabbit pAb from ELK Biotechnology Read more ›
VEGF Rabbit pAb is a research-use antibody from ELK Biotechnology for studying VEGF in IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38kDa or VEFGA110 34kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ). This antibody can recognize all VEGFA isoforms.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using VEGF（EA320）Rabbit pAb diluted at 1:500. | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using VEGF（ EA320 ）Rabbit pAb diluted at 1:500. | Immunohistochemical analysis of paraffin-embedded Human Stomach Carcinoma Tissue using VEGF（ EA320 ）Rabbit pAb diluted at 1:500. |
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| Collaborator | ELK Biotechnology |
| Partner model | EA320 |
| Target | VEGF |
| Research areas | Antibody Research |
| Reactivity | Human,Rat,Mouse |
| Applications | IHC |
| Conjugation | Unconjugated |
| Dilution range | IHC 1:200-500 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200-500 | — |
| Rat | — | — |
| Mouse | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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