VEGF Rabbit pAb
VEGF Rabbit pAb from ELK Biotechnology Read more ›
Product Description
VEGF Rabbit pAb is an ELK Biotechnology antibody for research workflows involving VEGF.
Background
VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38kDa or VEFGA110 34kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ). This antibody can recognize all VEGFA isoforms.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using VEGF（EA320）Rabbit pAb diluted at 1:500. | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using VEGF（ EA320 ）Rabbit pAb diluted at 1:500. | Immunohistochemical analysis of paraffin-embedded Human Stomach Carcinoma Tissue using VEGF（ EA320 ）Rabbit pAb diluted at 1:500. |
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Key Facts
| Target | VEGF |
| Also known as | VEGFA antibody, VPF antibody, VEGF120 antibody, Vascular endothelial growth factor antibody |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:200-500 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 23,45kDa |
| Cellular localization | Secreted |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:200-500 |
| Immunogen | Recombinant Protein |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200-500 | — |
| Rat | — | — |
| Mouse | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.