Primary Antibody supplied by Boster Bio Read more ›
Anti-Securin Monoclonal Antibody is a research-use antibody from Boster Bio for studying Securin in Flow Cytometry, IF/ICC, IHC, IP, WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
Boster Bio Anti-Securin Monoclonal Antibody catalog # M02099. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | M02099 |
| Product category | Primary Antibodies, Rabbit Monoclonal Antibodies |
| Reactive species | Human |
| Tested applications | Flow Cytometry, IF/ICC, IHC, IP, WB |
| Available conjugations | Unconjugated |
| Gene name | PTTG1 |
| Protein name | Securin |
| Immunogen | A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Purification | Affinity-chromatography |
| Storage | Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles. |
| UniProt | O95997 |
| NCBI Gene ID | 9232 |
| Conjugation | Size |
|---|---|
| Unconjugated | 100 μl/vial |
| Collaborator | Boster Bio |
| Partner model | M02099 |
| Target | Securin |
| Reactivity | Human |
| Applications | Flow Cytometry,IF/ICC,IHC,IP,WB |
| Conjugation | Unconjugated |
| Dilution range | WB 1:500-2000<br>IHC 1:50-200<br>ICC/IF 1:50-200<br>IP 1:30<br>FC 1:50<br> |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | Clone: ADFH-16 |
| Isotype | Rabbit IgG |
| Immunogen | A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. |
| Concentration | 0.5mg/ml |
| Purification | Affinity-chromatography |
| Shelf life | Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles. |
| Availability | Available |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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