Primary Antibody supplied by Boster Bio Read more ›
Anti-PITHD1 Antibody Picoband® is a research-use antibody from Boster Bio for studying PITH domain-containing protein 1 in ELISA, Flow Cytometry, IF/ICC, IHC, IHC-P, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Boster Bio Anti-PITHD1 Antibody Picoband® catalog # A15347-1. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.PITHD1 (PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1), also known as HT014, TXNL1CL or C1orf128, is a 211 amino acid nuclear protein containing one PITH domain. PITHD1 ectopic expression is thought to promote megakaryocytic differentiation and increase RUNX1 expression, while knockdown of PITHD1 was observed to have the opposite effect on both differentiation and RUNX1 expression. PITHD1 may regulate RUNX1 expression in two distinct fashions, by increasing transcription activity of proximal promoter and enhancing translational activity of an IRES element. Altered gene expression of the PITHD1 gene has been associated with leukemia development, with significant downregulation of expression observed in leukemic samples. The PITHD1 gene maps to chromosome 1 and is conserved in chimpanzee, Rhesus monkey, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C. e
| Collaborator | Boster Bio |
| Partner model | A15347-1 |
| Target | PITH domain-containing protein 1 |
| Reactivity | Human,Mouse,Rat |
| Applications | ELISA,Flow Cytometry,IF/ICC,IHC,IHC-P,WB |
| Conjugation | Unconjugated|Biotin|Cy3|Fluoro488|Fluoro550|Fluoro594|FITC|HRP|APC|PE|Fluoro647 |
| Dilution range | Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br> |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | E.coli-derived human PITHD1 recombinant protein (Position: C12-S211). Human PITHD1 shares 98% amino acid (aa) sequence identity with mouse PITHD1. |
| Concentration | Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
| Purification | Immunogen affinity purified. |
| Shelf life | At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing. |
| Availability | Available |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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