Primary Antibody supplied by Boster Bio Read more ›
Anti-P53 Tp53 Monoclonal Antibody is a research-use antibody from Boster Bio for studying Cellular tumor antigen p53 in IF/ICC, IHC, IHC-F, IHC-P, WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
Boster Bio Anti-P53 Tp53 Monoclonal Antibody catalog # MA1078. Tested in IHC, ICC, WB applications. This antibody reacts with Human.The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.
| Collaborator | Boster Bio |
| Partner model | MA1078 |
| Target | Cellular tumor antigen p53 |
| Reactivity | Human |
| Applications | IF/ICC,IHC,IHC-F,IHC-P,WB |
| Conjugation | Unconjugated |
| Cross-reactivity | No cross-reactivity with other proteins |
| Dilution range | Immunohistochemistry (Paraffin-embedded Section), 0.5-2μg/ml, Human <br>Immunocytochemistry , 1μg/ml, Human, -<br>Immunohistochemistry (Frozen Section), 0.5-2μg/ml, Human, -<br>Western blot, 0.5-1μg/ml, Human<br> |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Clone: BP53-12 |
| Isotype | Mouse IgG2a |
| Immunogen | Recombinant human wild-type p53 protein. |
| Concentration | Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml. |
| Purification | Ascites |
| Purity | No cross reactivity with other proteins. |
| Shelf life | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| Availability | Available |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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