Primary Antibody supplied by Boster Bio Read more ›
Potassium voltage-gated channel subfamily D member 3, also known as Kv4.3, is a protein that in humans is encoded by the KCND3 gene. KCND3 is a member of the potassium channel, voltage-gated, shal-related subfamily. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. It is mapped to 1p13.2. KCND3 is important in membrane repolarization in excitable cells. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
| Collaborator | Boster Bio |
| Partner model | PB9229 |
| Target | A-type voltage-gated potassium channel KCND3 |
| Reactivity | Human,Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | E.coli-derived human Kv4.3 recombinant protein (Position: M1-H177). Human Kv4.3 shares 100% and 99% amino acid (aa) sequences identity with mouse and rat Kv4.3, respectively. |
| Concentration | Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
| Purification | Immunogen affinity purified. |
| Purity | No cross reactivity with other proteins. |
| Shelf life | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | FLOW CYTOMETRY | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
