Primary Antibody supplied by Boster Bio Read more ›
Anti-JAK2 Monoclonal Antibody is a research-use antibody from Boster Bio for studying Tyrosine-protein kinase JAK2 in IF/ICC, IHC, IP, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Boster Bio Anti-JAK2 Monoclonal Antibody catalog # M00027. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | M00027 |
| Product category | Primary Antibodies, Rabbit Monoclonal Antibodies |
| Reactive species | Human, Mouse, Rat |
| Tested applications | IF/ICC, IHC, IP, WB |
| Available conjugations | Unconjugated |
| Gene name | JAK2 |
| Protein name | Tyrosine-protein kinase JAK2 |
| Immunogen | A synthesized peptide derived from human JAK2 Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Purification | Affinity-chromatography |
| Storage | Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles. |
| UniProt | O60674 |
| NCBI Gene ID | 3717 |
| Conjugation | Size |
|---|---|
| Unconjugated | 100 μl/vial |
| Collaborator | Boster Bio |
| Partner model | M00027 |
| Target | Tyrosine-protein kinase JAK2 |
| Reactivity | Human,Mouse,Rat |
| Applications | IF/ICC,IHC,IP,WB |
| Conjugation | Unconjugated |
| Dilution range | WB 1:500-2000<br>IHC 1:50-200<br>ICC/IF 1:50-200<br>IP 1:50-100<br> |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | Clone: COG-10 |
| Isotype | Rabbit IgG |
| Immunogen | A synthesized peptide derived from human JAK2 Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. |
| Concentration | 0.5mg/ml |
| Purification | Affinity-chromatography |
| Shelf life | Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles. |
| Availability | Available |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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