Primary Antibody supplied by Boster Bio Read more ›
Anti-c-Myc Antibody (Monoclonal, 9E10) is a research-use antibody from Boster Bio for studying Myc proto-oncogene protein in IF/ICC, IHC, IHC-P, WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
Boster Bio Anti-c-Myc Antibody (Monoclonal, 9E10) catalog # MA1028. Tested in IHC, ICC, WB applications. This antibody reacts with Human.C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
| Collaborator | Boster Bio |
| Partner model | MA1028 |
| Target | Myc proto-oncogene protein |
| Reactivity | Human |
| Applications | IF/ICC,IHC,IHC-P,WB |
| Conjugation | Unconjugated |
| Cross-reactivity | No cross-reactivity with other proteins |
| Dilution range | Immunohistochemistry (Paraffin-embedded Section), 5μg/ml, Human <br>Immunocytochemistry , 1μg/ml, Human, -<br>Western blot, 1μg/ml, Human<br> |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Clone: 9E10 |
| Isotype | Mouse IgG1 |
| Immunogen | Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein. |
| Concentration | Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml. |
| Purification | Ascites |
| Purity | No cross reactivity with other proteins. |
| Shelf life | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| Availability | Available |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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