ABM-27051
Anti-c-Myc Antibody (Monoclonal, 9E10)
ABMIUM Verified™|Collaborator Tested|Boster Bio
Primary Antibody supplied by Boster Bio Read more ›
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Product Description
Boster Bio Anti-c-Myc Antibody (Monoclonal, 9E10) catalog # MA1028. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | MA1028 |
| Product category | Primary Antibodies, Mouse Monoclonal Antibodies |
| Reactive species | Human |
| Tested applications | IF/ICC, IHC, IHC-P, WB |
| Available conjugations | Unconjugated |
| Gene name | MYC |
| Protein name | Myc proto-oncogene protein |
| Specificity | No cross reactivity with other proteins. |
| Immunogen | Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein. |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Purification | Ascites |
| Storage | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| UniProt | P09416 |
| NCBI Gene ID | Human(4609), Mouse(17869), Rat(24577) |
Available variants
| Conjugation | Size |
|---|---|
| Unconjugated | 100 μg/vial |
Key Facts
Product type
Primary Antibody›
Target: Myc proto-oncogene protein
| Target | Myc proto-oncogene protein |
| Also known as | C-Myc; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; Class E basic helix-loop-helix protein 39 |
| Concentration | Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml. |
| Species reactivity | Human |
| Observed band | 49 kDa |
| Purity | No cross reactivity with other proteins. |
| Form / buffer | Lyophilized |
| Shelf life | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| Host species | Mouse |
| Clonality | Monoclonal |
| Clone number | Clone: 9E10 |
| Isotype | Mouse IgG1 |
| Conjugation | Unconjugated |
| Non-cross-reactive with | No cross-reactivity with other proteins |
| Tested applications |
IF/ICCIHCIHC-PWB |
| Dilution range | Immunohistochemistry (Paraffin-embedded Section), 5μg/ml, Human Immunocytochemistry , 1μg/ml, Human, - Western blot, 1μg/ml, Human |
| Immunogen | Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein. |
| Purification | Ascites |
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Reactivity & Application Validation
1 species| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | FLOW CYTOMETRY | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
Specifications
Target
Myc proto-oncogene protein
Also known as
C-Myc; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; Class E basic helix-loop-helix protein 39
Concentration
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Purity
No cross reactivity with other proteins.
Form / buffer
Lyophilized
Host species
Mouse
Clonality
Monoclonal
Clone number
Clone: 9E10
Isotype
Mouse IgG1
Conjugation
Unconjugated
Species reactivity
Human
Tested applications
IF/ICCIHCIHC-PWB
Immunogen
Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein.
Observed band
49 kDa
Dilution range
Immunohistochemistry (Paraffin-embedded Section), 5μg/ml, Human
Immunocytochemistry , 1μg/ml, Human, -
Western blot, 1μg/ml, Human
Immunocytochemistry , 1μg/ml, Human, -
Western blot, 1μg/ml, Human
Purification
Ascites
Storage & Stability
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Shipped at
Ambient or cold-chain dependent on product format
Short-term storage
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Long-term storage
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Storage conditions
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Storage buffer
Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3. *This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Shelf life
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Compliance & Certifications
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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