a-actinin (4A12) Mouse mAb from ELK Biotechnology Read more ›
a-actinin (4A12) Mouse mAb is a research-use antibody from ELK Biotechnology for studying a-actinin (4A12) in IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Breast Carrcinoma Tissue using a-actinin（EM1261）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using a-actinin（EM1261）Mouse mAb diluted at 1:200. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1261 |
| Target | a-actinin (4A12) |
| Research areas | Antibody Research |
| Reactivity | Human,Rat,Mouse |
| Applications | IHC |
| Conjugation | Unconjugated |
| Dilution range | IHC 1:100-200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Recombinant Protein |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
| Rat | — | — |
| Mouse | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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