Recombinant Rat IL1R1/CD121a Protein (His & Fc Tag)
Recombinant Rat IL1R1/CD121a Protein (His & Fc Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measured by its ability to inhibit IL1α-dependent proliferation in D10.G4. 1 mouse helper T cells（Symons, J. A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M. J. et al. (eds): IRL Press. 272. ). The ED50 for this effect is typically 5-20 μg/ml in the presence of 40 pg/mL of recombinant human IL1a. ,90-95 kDa"]Product Description
IL1R1/CD121a is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Rat; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Rat ,IL1R1/CD121a ,Recombinant Proteins; predicted molecular weight: 64.6 kDa.
Quality and formulation: purity: > 85 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measured by its ability to inhibit IL1α-dependent proliferation in D10.G4. 1 mouse helper T cells（Symons, J. A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M. J. et al. (eds): IRL Press. 272. ). The ED<sub>50</sub> for this effect is typically 5-20 μg/ml in the presence of 40 pg/mL of recombinant human IL1a.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 64.6 kDa.
Database references: UniProt: NP_037255.3 | Gene symbol: IL1R1/CD121a.
Research Use Only.
Key Facts
| Target | IL1R1/CD121a |
| Also known as | CD121 antigen-like family member A, CD121A, D2S1473, IL-1 RI, IL-1R-1, IL-1R-alpha, IL-1R1, IL-1RT-1, IL-1RT1, IL1R, IL1RA, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, P80 |
| Species reactivity | Rat |
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Rat |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.