Recombinant Human Noggin/NOG Protein supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measured by its ability to inhibit BMP-4 induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 10-100ng/mL in the presence of 200 ng/mL of Recombinant Human BMP‑4(#CR93). ,25-33 kDa"]Noggin is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 2mM EDTA, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,Noggin ,Cytokines; predicted molecular weight: 23 kDa.
Quality and formulation: purity: > 95 % as determined by reducing SDS-PAGE.; endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measured by its ability to inhibit BMP-4 induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED<sub>50</sub> for this effect is 10-100ng/mL in the presence of 200 ng/mL of Recombinant Human BMP‑4(#CR93).. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 23 kDa.
Database references: UniProt: Q13253 | NCBI Gene: 9241 | Gene symbol: Noggin.
Research Use Only.
| Collaborator | Elabscience |
| Partner model | PKSH033576_10ug |
| Target | Noggin |
| Research areas | Developmental Biology, Stem cells |
| Reactivity | Human |
| Purity | >95% by SDS-PAGE |
| Endotoxin | < 0.01 EU per μg of the protein as determined by the LAL method. |
| Shelf life | 12 months |
| Availability | In stock - ships within 2 business days |
| Lead time | 2-3 business days |
| Category | Bioactivity | Binding | Cell-Based | In Vivo | ELISA Capture |
|---|---|---|---|---|---|
| Human |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
Environmental management certification.
Occupational health and safety management certification.
For research applications. Not for diagnostic use.
REACH compliant.
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