Recombinant Human IL-1 beta/IL1B Protein
Recombinant Human IL-1 beta/IL1B Protein supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measure by its ability to induce IL-8 secretion in HT29 cells. The ED50 for this effect is <2.0 ng/mL. The specific activity of recombinant human IL-1 beta is approximately >5 x 107 IU/mg. ,17 kDa"]Product Description
IL-1 beta is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: E.coli; physical form: Lyophilized from sterile PBS,pH 8.0.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL-1 beta ,Cytokines; predicted molecular weight: 18.5 kDa.
Quality and formulation: purity: > 98 % as determined by reducing SDS-PAGE.; endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measure by its ability to induce IL-8 secretion in HT29 cells. The ED<sub>50</sub> for this effect is <2.0 ng/mL. The specific activity of recombinant human IL-1 beta is approximately >5 x 10<sup>7</sup> IU/mg.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 18.5 kDa.
Database references: UniProt: P01584 | NCBI Gene: 3553 | Gene symbol: IL-1 beta.
Research Use Only.
Key Facts
| Target | IL-1 beta |
| Also known as | IL1F, IL-1F, pro IL1F, IL-1, IL1-BETA, IL1F2, IL1 beta, IL1B, catabolin, IL-1B, pro Catabolin, pro IL1B, pro IL1F2, pro leukocytic endogenous mediator, pro leukocytic pyrogen, pro lymphocyte activating factor, pro mononuclear cell factor, IL-1F2, IL 1B, IL-1 beta |
| Species reactivity | Human |
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from sterile PBS,pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| Research area | Cardiovascular, immunology, metabolism |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Human |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.