Recombinant Human IL1R2/CD121b Protein (His Tag)
Recombinant Human IL1R2/CD121b Protein (His Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["1. Measured by its ability to inhibit IL1β-dependent proliferation in D10.G4. 1 mouse helper T cells. The ED50 for this effect is typically 5. 5 μg/mL in the presence of 40 pg/mL of rhIL1β. 2. Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500pg/mL IL1b. The EC50 for this effect is typically 20-80ng/mL. ,50-55 kDa"]Product Description
IL1R2/CD121b is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL1R2/CD121b ,Recombinant Proteins; predicted molecular weight: 39.3 kDa.
Quality and formulation: purity: > 98 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: 1. Measured by its ability to inhibit IL1β-dependent proliferation in D10.G4. 1 mouse helper T cells. The ED<sub>50</sub> for this effect is typically 5. 5 μg/mL in the presence of 40 pg/mL of rhIL1β. 2. Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500pg/mL IL1b. The EC<sub>50</sub> for this effect is typically 20-80ng/mL.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 39.3 kDa.
Database references: UniProt: NP_004624.1 | NCBI Gene: 7850 | Gene symbol: IL1R2/CD121b.
Research Use Only.
Key Facts
| Target | IL1R2/CD121b |
| Also known as | IL1R, Interleukin-1 receptor type, IL-1R, IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, CD121 antigen-like family member B, IL-1 type II receptor, IL-1R-beta, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type I, IL-1R type II, IL-1RII |
| Species reactivity | Human |
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| Research area | Cardiovascular, immunology, Stem cells |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Human |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.