Home » Recombinant Human IL-1RA/IL1RN Protein
No reviews yet
Collaborator Elabscience
Recombinant ProteinsISO 9001:2015ISO 14001:2015ISO 45001:2018Collaborator Tested
ABM-16743

Recombinant Human IL-1RA/IL1RN Protein

1. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R2-FcThe EC50 of human IL1R2-Fc is 0.04-0.1 μg/mL. 2. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R1-FcThe EC50 of human IL1R1-Fc is 0.08-0.2 μg/mL. 3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL.E.coliPlease contact us for more information.

Recombinant Human IL-1RA/IL1RN Protein supplied by Elabscience with collaborator-provided technical specifications. Read more ›

Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL.
Zoom
Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL.["1. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R2-Fc, The EC50 of human IL1R2-Fc is 0.04-0.1 μg/mL. 2. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R1-Fc, The EC50 of human IL1R1-Fc is 0.08-0.2 μg/mL. 3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL. ,17.3 kDa"]

Product Description

IL-1RA/IL1RN is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.

Protein profile: reactive species/source: Human; expression system: E.coli; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL-1RA/IL1RN ,Recombinant Proteins; predicted molecular weight: 17.3 kDa.

Quality and formulation: purity: > 97 % as determined by reducing SDS-PAGE..

Functional evidence: activity: 1. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R2-Fc, The EC<sub>50</sub> of human IL1R2-Fc is 0.04-0.1 μg/mL. 2. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R1-Fc, The EC<sub>50</sub> of human IL1R1-Fc is 0.08-0.2 μg/mL. 3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC<sub>50</sub> for this effect is typically 3-12 ng/mL.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.

Sequence coverage: 17.3 kDa.

Database references: UniProt: NP_776214.1 | NCBI Gene: 3557 | Gene symbol: IL-1RA/IL1RN.

Research Use Only.

Key Facts

Product typeRecombinant Proteins› Target: IL-1RA/IL1RN
IL-1RA/IL1RNUniProt: NP_776214.1Gene ID: 3557
Collaborator Elabscience
Partner model PKSH031854_100ug
Target IL-1RA/IL1RN
Research areasimmunology
Reactivity Human
Purity >97% by SDS-PAGE
Shelf life 12 months
AvailabilityIn stock - ships within 2 business days
Lead time2-3 business days
Why ABMIUM?
2,000+ Researchers trust us
50,000+ Citations
ISO 9001 Certified Collaborators
Independently handpicked Products selected for quality and fit

Validation Matrix

1 category
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
CategoryBioactivityBindingCell-BasedIn VivoELISA Capture
Human

Specifications

Target
IL-1RA/IL1RN
Also known as
IL1F, MVCD, IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4, Anakinra, IL1 inhibitor, Interleukin-1 receptor antagonist protein, F630041P17Rik, ICIL 1RA, ICIL1RA, IL1RN (IL1F3), Interleukin 1 receptor antagonist, Intracellular IL 1 receptor antagonist type II, Intracellular interleukin 1 receptor antagonist (icIL 1ra), MGC10430, Type II interleukin 1 receptor antagonist
Purity
>97% by SDS-PAGE
Form / buffer
Lyophilized

Storage & Stability

Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting advice
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Shelf life
12 months

Compliance & Certifications

ABMIUM
ABMIUM Verified™

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001:2015

Quality management certification.

ISO
ISO 14001:2015

Environmental management certification.

ISO
ISO 45001:2018

Occupational health and safety management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

REACH
REACH

REACH compliant.

Customer Reviews

No customer reviews yet.