Recombinant Human FLT1 Protein (aa 1-328, His Tag)

Immobilized Recombinant Human VEGFR1 / FLT-1 Protein (His Tag) (Cat: PKSH031841) at 2 μg/mL (100 μL/well) can bind Recombinant Human / Cynomolgus VEGF / VEGFA / VEGF165 Protein (Cat: PKSH031978), the EC50 is 9.7-29.3 ng/mL.

Immobilized Recombinant Human VEGFR1 / FLT-1 Protein (His Tag) (Cat: PKSH031841) at 2 μg/mL (100 μL/well) can bind Recombinant Human / Cynomolgus VEGF / VEGFA / VEGF165 Protein (Cat: PKSH031978), the EC<sub>50</sub> is 9.7-29.3 ng/mL.
Manufactured by:Elabscience
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Recombinant Human FLT1 Protein (aa 1-328, His Tag)

Recombinant Human FLT1 Protein (aa 1-328, His Tag) supplied by Elabscience with collaborator-provided technical specifications.

SKU:
ABM16731
Product type
Recombinant Proteins
TargetFLT1
Species / reactivityHuman
Purity>90% by SDS-PAGE

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human FLT1 Protein (aa 1-328, His Tag) is a research-use recombinant protein from Elabscience preparation representing FLT1 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Signal Transduction, Cardiovascular, Cancer, metabolism
Also known as
FLT, FLT-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGFR-1, VEGFR1 , Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
Modification
C-His
Molecular weight
35.6 kDa
Form / buffer
Lyophilized
Activity
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells ( HUVEC ). The ED50 for this effect is typically 10-40 ng/mL in the presence of 10 ng/mL human VEGF165.
Endotoxin level
< 1.0 EU per μg of the protein as determined by the LAL method.
Sequence
Met 1-Ile328
Technical note
Please refer to the printed manual for detailed information.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioactivityBindingCell-BasedIn VivoELISA Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PKSH031841_100ug
Gene symbol
FLT1
Gene ID
2321
UniProt accession
NP_002010.2
Storage, stability & shipping
Shelf life
12 months
Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting guidance
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

FLT1fms related receptor tyrosine kinase 1

View target guide

Fms related receptor tyrosine kinase 1 (FLT1), also known as vascular endothelial growth factor receptor 1 (VEGFR1), is a VEGF-family receptor. This ABMIUM record links human FLT1 (NCBI Gene 2321; UniProt P17948) to catalogue-backed products.

Biological function: FLT1/VEGFR1 is a receptor tyrosine kinase that binds vascular endothelial growth factor ligands and placental growth factor. It contributes to angiogenesis and vasculogenesis, with membrane-bound and soluble receptor isoforms.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
2321
UniProtKB
P17948
Browse all FLT1 productsRead target context & evidence
Elabscience
£507.00£405.60