Collaborator Elabscience
Recombinant ProteinsISO 9001:2015ISO 14001:2015ISO 45001:2018Collaborator Tested
ABM-16714

Recombinant Human CSF1R/CD115 Protein (aa 1-512, His Tag)

1. Immobilized human CSF1R at 10 μg/mL (100 μl/well) can bind biotinylated human CSF-1The EC50 of biotinylated human CSF-1 is 8 ng/mL.
2. Measured by its ability to inhibit the human CSF-induced proliferation of M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 6-30 μg/mL in the presence of 3 ng/ml Recombinant Human M-CSF.
HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.

Recombinant Human CSF1R/CD115 Protein (aa 1-512, His Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›

> 98 % as determined by reducing SDS-PAGE.
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> 98 % as determined by reducing SDS-PAGE.["1. Immobilized human CSF1R at 10 μg/mL (100 μl/well) can bind biotinylated human CSF-1, The EC50 of biotinylated human CSF-1 is 8 ng/mL.
2. Measured by its ability to inhibit the human CSF-induced proliferation of M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 6-30 μg/mL in the presence of 3 ng/ml Recombinant Human M-CSF. ,85-95 kDa"]

Product Description

CSF1R/CD115 is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.

Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,CSF1R/CD115 ,Recombinant Proteins; predicted molecular weight: 56.0 kDa.

Quality and formulation: purity: > 98 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..

Functional evidence: activity: 1. Immobilized human CSF1R at 10 μg/mL (100 μl/well) can bind biotinylated human CSF-1, The EC<sub>50</sub> of biotinylated human CSF-1 is 8 ng/mL. <br/>2. Measured by its ability to inhibit the human CSF-induced proliferation of M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED<sub>50</sub> for this effect is typically 6-30 μg/mL in the presence of 3 ng/ml Recombinant Human M-CSF.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.

Sequence coverage: 56.0 kDa.

Database references: UniProt: NP_005202.2 | NCBI Gene: 1436 | Gene symbol: CSF1R/CD115.

Research Use Only.

Key Facts

Product typeRecombinant Proteins Target: CSF1R/CD115
Collaborator Elabscience
Partner model PKSH031819_100ug
Target CSF1R/CD115
Research areasSignal Transduction, Cardiovascular, immunology
Reactivity Human
Purity >98% by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Shelf life 12 months
AvailabilityIn stock - ships within 2 business days
Lead time2-3 business days
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Validation Matrix

1 category
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
CategoryBioactivityBindingCell-BasedIn VivoELISA Capture
Human

Specifications

Target
CSF1R/CD115
Also known as
C-FMS, CD115, CSF-1 receptor, CSF-1-R, CSF-1R, CSF1R, FIM2, FMS, HDLS, M-CSF-R, MCSF Receptor , Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms
Purity
>98% by SDS-PAGE
Form / buffer
Lyophilized

Storage & Stability

Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting advice
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Shelf life
12 months

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001:2015

Quality management certification.

ISO
ISO 14001:2015

Environmental management certification.

ISO
ISO 45001:2018

Occupational health and safety management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

REACH
REACH

REACH compliant.

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