Cytokines ISO 9001:2015ISO 14001:2015ISO 45001:2018ABMIUM Verified™Collaborator Tested
ABM-16561

Recombinant Human IL5RA/IL-5 Rα Protein (His Tag)

1. Immobilized recombinant mouse IL5-his at 5 μg/mL (100 μL/well) can bind biotinylated human IL5Ra-his with a linear range of 32-4000 ng/mL. 2. Measured by its ability to inhibit IL5 dependent proliferation of TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.7-2. 8 μg/mL.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.

Recombinant Human IL5RA/IL-5 Rα Protein (His Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›

Related formats
> 85 % as determined by reducing SDS-PAGE.
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> 85 % as determined by reducing SDS-PAGE.["1. Immobilized recombinant mouse IL5-his at 5 μg/mL (100 μL/well) can bind biotinylated human IL5Ra-his with a linear range of 32-4000 ng/mL. 2. Measured by its ability to inhibit IL5 dependent proliferation of TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.7-2. 8 μg/mL. ,45-50 kDa"]

Product Description

IL5RA/IL-5 is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.

Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL5RA/IL-5 ,Cytokines; predicted molecular weight: 37.3 kDa.

Quality and formulation: purity: > 85 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..

Functional evidence: activity: 1. Immobilized recombinant mouse IL5-his at 5 μg/mL (100 μL/well) can bind biotinylated human IL5Ra-his with a linear range of 32-4000 ng/mL. 2. Measured by its ability to inhibit IL5 dependent proliferation of TF1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is typically 0.7-2. 8 μg/mL.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.

Sequence coverage: 37.3 kDa.

Database references: UniProt: Q01344-2 | NCBI Gene: 3568 | Gene symbol: IL5RA/IL-5.

Research Use Only.

Key Facts

Product type Cytokines Target: IL5RA/IL-5
Target IL5RA/IL-5
Also known as CDw, HSIL5R, IL5RA, CD125, CDw125, HSIL5R3, IL5R, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5RA, IL-5R-alpha, Interleukin-5 receptor subunit alpha, CDw125, IL-5R&, alpha, CD125 antigen, IL5R, Interleukin 5 Receptor alpha, Interleukin 5 Receptor alpha chain, Interleukin 5 receptor alpha subunit, Interleukin 5 receptor subunit alpha, Interleukin 5 receptor type 3, MGC26560
Species reactivity Human
Purity > 85 % as determined by reducing SDS-PAGE.
Form / buffer Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Shelf life 12 months
Research area Immunology
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1
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
BIOACTIVITYBINDINGCELL-BASEDIN VIVOELISA CAPTURE
Human

Specifications

Target
IL5RA/IL-5
Also known as
CDw, HSIL5R, IL5RA, CD125, CDw125, HSIL5R3, IL5R, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5RA, IL-5R-alpha, Interleukin-5 receptor subunit alpha, CDw125, IL-5R&, alpha, CD125 antigen, IL5R, Interleukin 5 Receptor alpha, Interleukin 5 Receptor alpha chain, Interleukin 5 receptor alpha subunit, Interleukin 5 receptor subunit alpha, Interleukin 5 receptor type 3, MGC26560
Purity
> 85 % as determined by reducing SDS-PAGE.
Form / buffer
Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Storage & Stability

Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting advice
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Shelf life
12 months

Compliance & Certifications

ISO 9001:2015
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

ISO 14001:2015
ISO 14001:2015 Certified

Manufactured under ISO 14001:2015 quality management standards.

ISO 45001:2018
ISO 45001:2018 Certified

Manufactured under ISO 45001:2018 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

REACH
REACH Compliant

Substance does not appear on the SVHC candidate list.

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