Recombinant Human TRAIL R4/TNFRSF10D Protein (His Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["1. Immobilized human TNFRSF10D at 10 μg/ml (100 μl/well) can bind biotinylated TNFSF10 with a linear range of 0.625-40 ng/ml. 2. Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L‑929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is typically 0.05-0.5 μg/mL in the presence of 20 ng/ml Recombinant Human TRAIL/TNFSF10. ,30-40 kDa"]TRAIL R4/TNFRSF10D is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,TRAIL R4/TNFRSF10D ,Recombinant Proteins; predicted molecular weight: 18.4 kDa.
Quality and formulation: purity: > 90 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: 1. Immobilized human TNFRSF10D at 10 μg/ml (100 μl/well) can bind biotinylated TNFSF10 with a linear range of 0.625-40 ng/ml. 2. Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L‑929 mouse fibroblast cells treated with TRAIL. The ED<sub>50</sub> for this effect is typically 0.05-0.5 μg/mL in the presence of 20 ng/ml Recombinant Human TRAIL/TNFSF10.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 18.4 kDa.
Database references: UniProt: NP_003831.2 | NCBI Gene: 8793 | Gene symbol: TRAIL R4/TNFRSF10D.
Research Use Only.
| Collaborator | Elabscience |
| Partner model | PKSH031621_100ug |
| Target | TRAIL R4/TNFRSF10D |
| Research areas | Cell biology, Cancer, immunology |
| Reactivity | Human |
| Purity | >90% by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Shelf life | 12 months |
| Availability | In stock - ships within 2 business days |
| Lead time | 2-3 business days |
| Category | Bioactivity | Binding | Cell-Based | In Vivo | ELISA Capture |
|---|---|---|---|---|---|
| Human |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
Environmental management certification.
Occupational health and safety management certification.
For research applications. Not for diagnostic use.
REACH compliant.
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