Recombinant Human IL6ST/CD130 Protein (His & Fc Tag)
Recombinant Human IL6ST/CD130 Protein (His & Fc Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measured by its ability to inhibit the IL-6Rα enhancement of IL-6 activity on M1 mouse myeloid leukemia cell. The ED50 for this effect is typically 0.2-0.8 μg/mL in the presence of 50 ng/mL recombinant human IL-6sR and 100 ng/mL recombinant human IL-6. ,125-140 kDa"]Product Description
IL6ST/CD130 is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL6ST/CD130 ,Recombinant Proteins; predicted molecular weight: 96.0 kDa.
Quality and formulation: purity: > 95 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measured by its ability to inhibit the IL-6Rα enhancement of IL-6 activity on M1 mouse myeloid leukemia cell. The ED<sub>50</sub> for this effect is typically 0.2-0.8 μg/mL in the presence of 50 ng/mL recombinant human IL-6sR and 100 ng/mL recombinant human IL-6.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 96.0 kDa.
Database references: UniProt: NP_002175.2 | NCBI Gene: 3572 | Gene symbol: IL6ST/CD130.
Research Use Only.
Key Facts
| Target | IL6ST/CD130 |
| Also known as | CDW, IL6ST, CD130, CDW130, GP130, IL-6RB, Interleukin 6 signal transducer, IR6RB, CD130 antigen, GP130 RAPS, IL 6R beta, IL-6 receptor subunit beta, IL6 ST, IL-6R subunit beta, IL6RB, IL-6R-beta, Interleukin 6 receptor subunit beta, Interleukin receptor beta chain, Interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, Membrane glycoprotein gp130, Oncostatin M receptor, Oncostatin M receptor alpha subunit, Oncostatin-M receptor subunit alpha |
| Species reactivity | Human |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| Research area | Signal Transduction, Cell biology, Cardiovascular, Cancer, immunology, |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Human |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.