Anticorps primaire fourni par Boster Bio
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La désacétylase dépendante du NAD sirtuine-3, mitochondriale, également connue sous le nom de SIRT3, est une protéine qui, chez l'homme, est codée par le gène SIRT3. SIRT3 code pour un membre de la famille des sirtuines des histones désacétylases de classe III, homologues de la protéine Sir2 de la levure. La protéine codée se trouve exclusivement dans les mitochondries, où elle peut éliminer les espèces réactives de l'oxygène, inhiber l'apoptose et prévenir la formation de cellules cancéreuses. SIRT3 a des effets de grande portée sur l'expression génique nucléaire, le cancer, les maladies cardiovasculaires, la neuroprotection, le vieillissement et le contrôle métabolique.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.