Manufactured by:Elabscience
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Human AhR (Aryl Hydrocarbon Receptor) CLIA Kit

Human AhR (Aryl Hydrocarbon Receptor) CLIA Kit with collaborator-tested sample matrix evidence from Elabscience.

SKU:
ABM10934-1
Product type
Assay Kits
TargetAhR

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Human AhR (Aryl Hydrocarbon Receptor) CLIA Kit from Elabscience is intended for research workflows involving AhR. Review the listed specifications and supporting documents to confirm compatibility with the intended method.

Key facts & specifications
Research areas
Cancer, Epigenetics and Nuclear Signaling
Cross-reactivity
This kit recognizes Human AhR in samples.No significant cross-reactivity or interference between Human AhR and analogues was observed
Incubation temperature
2-8℃/-20℃
Assay type
CLIA Kits
Detection method
Chemiluminescence
Plate format
48-well microplate plates pre-coated with anti-AhR capture antibody
Technical note
This CLIA kit uses the Sandwich-CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human AhR. Samples or Standards are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human AhR and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human AhR, biotinylated detection antibody and Avidin-HRP conjugate will appear luminescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer at 425nm. The RLU value is positively associated with the concentration of Human AhR. You can calculate the concentration of Human AhR in the samples by comparing the RLU value of the samples to the standard curve.
Identifiers & database references
Supplier SKU / catalogue number
E-CL-H0410_48T
Gene symbol
AhR
Gene ID
196
UniProt accession
P35869
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
4 degrees C for up to 6 months; do not freeze pre-coated plate
Long-term storage
4 degrees C for up to 12 months
Aliquoting guidance
Lyophilised standards and detection antibody may be reconstituted and aliquoted; store reconstituted aliquots at -20 degrees C for up to 2 weeks
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

AHRaryl hydrocarbon receptor

View target guide

AHR is the aryl hydrocarbon receptor, also known as AhR or Ah receptor. This ligand-activated transcription factor senses diverse environmental, dietary, microbial and endogenous compounds and converts ligand binding into regulated gene-expression programmes.

Biological function: AHR is a ligand-activated basic helix-loop-helix transcription factor. After ligand binding it translocates to the nucleus, heterodimerizes with ARNT and binds xenobiotic-response elements to regulate target genes, including xenobiotic-metabolising enzymes such as CYP1A1. AHR signalling also contributes to broader developmental, metabolic and immune regulatory programmes.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
196
UniProtKB
P35869
Elabscience
£407.00£325.60