Primärantikörper geliefert von Boster Bio
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TFPI (Tissue Factor Pathway Inhibitor), auch bekannt als EPI, LACI, TFI und TFPT1, ist ein einzelnes Polypeptid, das Faktor Xa (Xa) und Thrombin (Faktor IIa) reversibel hemmen kann. Während Xa gehemmt wird, kann der Xa-TFPI-Komplex anschließend auch den FVIIa-Tissue-Factor-Komplex hemmen. TFPI trägt signifikant zur Hemmung von Xa in vivo bei, obwohl es nur in Konzentrationen von 2,5 nM vorhanden ist. Das Gen für TFPI befindet sich auf Chromosom 2q31-q32.1 und hat neun Exons, die sich über 70 kb erstrecken. TFPI hat eine relative Molekülmasse von 34.000 bis 40.000, abhängig vom Grad der Proteolyse der C-terminalen Region.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.