Primärantikörper geliefert von Boster Bio
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PXYLP1 dephosphoryliert den Xylose (Xyl)-Rest in der Glykosaminoglykan (GAG)-Protein-Verknüpfungsregion von Proteoglykanen, was für die biosynthetische Reifung der Verknüpfungsregion erforderlich ist. Verantwortlich für die 2-O-Dephosphorylierung von Xylose in der Glykosaminoglykan-Protein-Verknüpfungsregion von Proteoglykanen, wodurch die Menge an reifen Glykosaminoglykan (GAG)-Ketten reguliert wird. Sulfatierte Glykosaminoglykane (GAGs), einschließlich Heparansulfat und Chondroitinsulfat, werden an der sogenannten gemeinsamen GAG-Protein-Verknüpfungsregion (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) von Kernproteinen synthetisiert, die durch die schrittweise Addition von Monosaccharidresten durch die jeweiligen spezifischen Glykosyltransferasen gebildet wird. Die Xylose-2-O-Dephosphorylierung während der Vervollständigung der Verknüpfungsregionsbildung ist eine Voraussetzung für die Initiierung und effiziente Verlängerung der sich wiederholenden Disaccharidregion von GAG-Ketten.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.