Primärantikörper von Boster Bio
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Protection of telomeres protein 1 ist ein Protein, das beim Menschen vom POT1-Gen kodiert wird. Dieses Gen gehört zur Telombin-Familie und kodiert ein nukleäres Protein, das an der Telomerwartung beteiligt ist. Insbesondere fungiert dieses Protein als Mitglied eines Multiproteinkomplexes, der an die TTAGGG-Wiederholungen der Telomere bindet, die Telomerlänge reguliert und die Chromosomenenden vor illegitimer Rekombination, katastrophaler Chromosomeninstabilität und abnormaler Chromosomensegregation schützt. Eine erhöhte transkriptionelle Expression dieses Gens ist mit der Magenkarzinogenese und deren Progression verbunden. Alternativ gespleißte Transkriptvarianten wurden beschrieben.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.