Primärantikörper von Boster Bio
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Die Protein-L-isoaspartat(D-aspartat)-O-Methyltransferase ist ein Enzym, das beim Menschen durch das PCMT1-Gen kodiert wird. Dieses Gen kodiert ein Mitglied der Typ-II-Klasse der Proteincarboxyl-Methyltransferase-Enzyme. Das kodierte Enzym spielt eine Rolle bei der Proteinreparatur, indem es D-Aspartyl- und L-Isoaspartylreste, die durch spontane Deamidierung entstehen, erkennt und in die normale L-Aspartylform zurückführt. Das kodierte Protein könnte eine schützende Rolle bei der Pathogenese der Alzheimer-Krankheit spielen, und Einzelnukleotid-Polymorphismen in diesem Gen wurden mit Spina bifida und vorzeitigem Ovarialversagen in Verbindung gebracht. Alternativ gespleißte Transkriptvarianten, die mehrere Isoformen kodieren, wurden für dieses Gen beobachtet.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Mensch | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
