Primärer Antikörper geliefert von Boster Bio
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NPC2 ist ein Protein, das mit der Niemann-Pick-Krankheit Typ C assoziiert ist. Dieses Gen ist auf Chromosom 14q24.3 kartiert. Es kodiert ein Protein, das eine Lipiderkennungsdomäne enthält. Das kodierte Protein kann die Regulation des Cholesterintransports durch das Spätendosomen-/Lysosomensystem übernehmen. Mutationen in diesem Gen wurden mit der Niemann-Pick-Krankheit Typ C2 und frontaler Lappenatrophie in Verbindung gebracht.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.