Primärantikörper geliefert von Boster Bio
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Dieses Gen kodiert einen nukleären Rezeptor-Co-Repressor, der die transkriptionelle Stilllegung bestimmter Zielgene vermittelt. Das kodierte Protein ist Mitglied einer Familie von Schilddrüsenhormon- und Retinsäure-Rezeptor-assoziierten Co-Repressoren. Dieses Protein agiert als Teil eines Multisubunit-Komplexes, der Histondeacetylasen umfasst, um die Chromatin-Struktur zu modifizieren, die die basale transkriptionelle Aktivität von Zielgenen verhindert. Eine aberrante Expression dieses Gens ist mit bestimmten Krebsarten assoziiert. Alternatives Splicing führt zu mehreren Transkriptvarianten, die verschiedene Isoformen kodieren.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
