Primärantikörper geliefert von Boster Bio
Know who made it. See the evidence. Buy through one marketplace.
O6-Alkylguanin-DNA-Alkyltransferase (auch bekannt als AGT, MGMT oder AGAT) ist ein Protein, das beim Menschen durch das O6-Methylguanin-DNA-Methyltransferase (MGMT)-Gen kodiert wird. MGMT ist auf 10q26.3 kartiert. Dieses Gen ist entscheidend für die Genomstabilität. Es repariert die natürlich vorkommende mutagene DNA-Läsion O6-Methylguanin zurück zu Guanin und verhindert Fehlanpassungen und Fehler während der DNA-Replikation und -Transkription. Es wurde festgestellt, dass die Methylierung des MGMT-Promoters im Tumor mit einem längeren Überleben verbunden war.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.