Primärantikörper geliefert von Boster Bio
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Inosin-Triphosphat-Pyrophosphatase ist ein Enzym, das beim Menschen vom ITPA-Gen, bei Bakterien E. coli vom rdgB-Gen und bei Hefe S. cerevisiae vom HAM1-Gen kodiert wird; das Protein wird auch von einigen RNA-Viren der Familie Potyviridae kodiert. Dieses Gen kodiert eine Inosin-Triphosphat-Pyrophosphohydrolase. Das kodierte Protein hydrolysiert Inosin-Triphosphat und Desoxyinosin-Triphosphat zu dem Monophosphat-Nukleotid und Diphosphat. Dieses Protein, das ein Mitglied der HAM1 NTPase-Proteinfamilie ist, findet sich im Zytoplasma und agiert als Homodimer. Defekte in dem kodierten Protein können zu einem Inosin-Triphosphat-Pyrophosphorylase-Mangel führen, der eine Akkumulation von ITP in roten Blutkörperchen verursacht. Alternatives Spleißen führt zu mehreren Transkriptvarianten.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
