Primärantikörper geliefert von Boster Bio
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Dieses Gen kodiert ein Mitglied der Cytochrom-P450-Superfamilie von Enzymen. Die Cytochrom-P450-Proteine sind Monooxygenasen, die viele Reaktionen katalysieren, die am Arzneimittelstoffwechsel und an der Synthese von Cholesterin, Steroiden und anderen Lipiden beteiligt sind. Und dieses mitochondriale Protein leitet den Abbau von 1,25-Dihydroxyvitamin D3, der physiologisch aktiven Form von Vitamin D3, durch Hydroxylierung der Seitenkette ein. Bei der Regulierung des Vitamin-D3-Spiegels spielt dieses Enzym eine Rolle bei der Kalziumhomöostase und dem Vitamin-D-endokrinen System. Alternativ gespleißte Transkriptvarianten, die verschiedene Isoformen kodieren, wurden für dieses Gen gefunden.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.