Primärantikörper geliefert von Boster Bio
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Cyclin-abhängige Kinase-4 (CDK4) ist eine Protein-Serin-Kinase, die am Zellzyklus beteiligt ist. Die menschliche Zellteilung wird hauptsächlich an den G1-zu-S- oder G2-zu-M-Grenzen innerhalb des Zellzyklus reguliert. Die Komplexe, die von CDK4 und den D-Typ-Cyclinen gebildet werden, sind an der Kontrolle der Zellproliferation während der G1-Phase beteiligt. CDK4 wird durch p16, auch bekannt als Cyclin-abhängiger Kinase-Inhibitor-2, gehemmt. CDK4 ist auf 12q14 kartiert. Die Expression und Aktivität von CDK4 sind für die Zytokin-Antwortfähigkeit in T-Zellen erforderlich.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.