Primärantikörper geliefert von Boster Bio
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CDK2, Cyclin-Dependent Kinase2, ist auch als P33 bekannt. Das CDK2-Protein war hochhomolog zu p34 (CDC2) Kinase und noch signifikanter homolog zu Xenopus Eg1 Kinase, was darauf hindeutet, dass CDK2 das menschliche Homolog von Eg1 ist. Das CDK2-Gen ist auf 12q13 kartiert, der gleichen Region, auf die das CDK4-Gen kartiert ist. Humanes Cyclin A bindet unabhängig an 2 Kinasen, p34 (cdc2) oder p33. In Adenovirus-transformierten Zellen scheint das virale E1A-Onkoprotein mit p33/Cyclin A zu assoziieren, aber nicht mit p34 (cdc2)/Cyclin A. Das Gen für p33 weist eine 65%ige Sequenzidentität mit p34 (cdc2) auf. P33 (cdk2) spielt eine einzigartige Rolle bei der Zellzyklusregulation von Wirbeltierzellen.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
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