Primärantikörper geliefert von Boster Bio
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CD137 ist ein Mitglied der Tumornekrosefaktor (TNF)-Rezeptorfamilie. Dieser Rezeptor trägt zur klonalen Expansion, zum Überleben und zur Entwicklung von T-Zellen bei. Er kann auch die Proliferation in peripheren Monozyten induzieren, die TCR/CD3-getriggerte T-Zell-Apoptose verstärken und die CD28-Co-Stimulation regulieren, um Th1-Zellantworten zu fördern. Die Expression dieses Rezeptors wird durch Lymphozytenaktivierung induziert. Es wurde gezeigt, dass TRAF-Adapterproteine an diesen Rezeptor binden und die Signale transduzieren, die zur Aktivierung von NF-kappaB führen.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.