Primärantikörper geliefert von Boster Bio
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Die de-novo-Synthese von Pyrimidin-Nukleotiden ist für die Proliferation von Säugetierzellen erforderlich. Dieses Gen kodiert ein trifunktionales Protein, das mit den enzymatischen Aktivitäten der ersten 3 Enzyme im 6-stufigen Pyrimidin-Biosyntheseweg assoziiert ist: Carbamoylphosphat-Synthetase (CPS II), Aspartat-Transcarbamoylase und Dihydroorotase. Dieses Protein wird durch die Mitogen-aktivierte Proteinkinase (MAPK)-Kaskade reguliert, was auf eine Verbindung zwischen der Aktivierung der MAPK-Kaskade und der de-novo-Biosynthese von Pyrimidin-Nukleotiden hinweist. Alternatives Spleißen führt zu mehreren Transkriptvarianten, die verschiedene Isoformen kodieren.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
