Manufactured by:Elabscience
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Rekombinantes menschliches ACE2-Protein (Fc-Tag)

Rekombinantes menschliches ACE2-Protein (Fc-Tag), geliefert von Elabscience mit vom Kooperationspartner bereitgestellten technischen Spezifikationen.

SKU:
ABM20175-1
Product type
Rekombinante Proteine
TargetACE2
Species / reactivityMensch
Purity> 95 % bestimmt mittels reduzierender SDS-PAGE.

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human ACE2 Protein (Fc Tag) is a research-use recombinant protein from Elabscience preparation representing ACE2 supplied as Liquid. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Cell biology, Cardiovascular
Also known as
ACE-bezogene Carboxypeptidase, ACE2, ACEH, Angiotensin-konvertierendes Enzym 2, Angiotensin-konvertierendes Enzym Homolog, Metalloprotease MPROT15
Modification
C-Fc
Molecular weight
110,5 kDa
Concentration
Vorbehaltlich des Kennzeichnungswertes.
Form / buffer
Geliefert als 0,2 μm filtrierte Lösung von 20mM Tris-HCl, 300mM NaCl, 10% Glycerin, 100mM Glycin, pH 7,4.
Activity
Immobilisiertes humanes ACE-2-Fc (Kat.-Nr. PKSR030492) bei 2 μg/ml (100 μl/Well) kann 2019-nCoV S Protein RBD-SD1-mFc (Kat.-Nr. PKSR030476) binden. Die ED50 von rekombinantem 2019-nCoV S Protein RBD-mFc (Kat.-Nr. PKSR030476) beträgt 15,5 ng/ml.
Endotoxin level
< 1,0 EU pro μg des Proteins, bestimmt nach der LAL-Methode.
Sequence
Gln18-Ser740
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioaktivitätBindungZellbasiertIn VivoELISA-Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PKSR030492_10ug
Gene symbol
ACE2
Gene ID
59272
UniProt accession
Q9BYF1
Storage, stability & shipping
Shelf life
6 Monate
Shipped at
Dieses Produkt wird als Flüssigkeit geliefert. Es wird bei Gefriertemperatur mit Kühlakkus/Gelpacks versandt. Nach Erhalt sofort bei < - 20°C lagern.
Short-term storage
Bei < -20°C lagern, 6 Monate stabil. Bitte Gefrier-Tau-Zyklen minimieren.
Long-term storage
Bei < -20°C lagern, 6 Monate stabil. Bitte Gefrier-Tau-Zyklen minimieren.
Aliquoting guidance
Den gesamten Flascheninhalt sofort rekonstituieren. Arbeitslösung aliquotieren; wiederholtes Einfrieren und Auftauen vermeiden.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

ACE2angiotensin converting enzyme 2

View target guide

Angiotensin-converting enzyme 2 (ACE2; also known as ACEH) is a membrane-associated metallopeptidase in the renin-angiotensin system. This target record connects human NCBI Gene 59272, reviewed UniProtKB Q9BYF1 and related ABMIUM catalogue products.

Biological function: Angiotensin-converting enzyme 2 (ACE2) is a counter-regulatory carboxypeptidase of the renin-angiotensin system. It converts angiotensin I to angiotensin-(1-9) and angiotensin II to angiotensin-(1-7), helping counterbalance classical angiotensin II signalling and supporting cardiovascular homeostasis. ACE2 also functions as a cellular receptor for HCoV-NL63, SARS-CoV and SARS-CoV-2 spike proteins.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
59272
UniProtKB
Q9BYF1
Elabscience
£66.00£52.80