Rekombinantes humanes Noggin/NOG Protein (His-Tag)

Measured by its ability to inhibit recombinant human BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 10-60 ng/mL in the presence of 25 ng/mL of recombinant human BMP4.

Measured by its ability to inhibit recombinant human BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED<sub>50</sub> for this effect is typically 10-60 ng/mL in the presence of 25 ng/mL of recombinant human BMP4.
Manufactured by:Elabscience
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Rekombinantes humanes Noggin/NOG Protein (His-Tag)

Rekombinantes humanes Noggin/NOG Protein (His-Tag) geliefert von Elabscience mit technischen Spezifikationen des Kollaborators.

SKU:
ABM16626-1
Product type
Rekombinante Proteine
TargetNoggin/NOG
Species / reactivityMensch
Purity> 95 % laut reduzierender SDS-PAGE.

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human Noggin/NOG Protein (His Tag) is a research-use recombinant protein from Elabscience preparation representing Noggin/NOG supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Developmental Biology, Stem cells
Also known as
Noggin, SYM1, SYNS1
Modification
C-His
Molecular weight
24,6 kDa
Form / buffer
Lyophilisiert aus sterilem PBS, pH 7,4
Vor der Lyophilisation werden normalerweise 5 % - 8 % Trehalose, Mannitol und 0,01 % Tween 80 als Schutzmittel zugesetzt.
Bitte beachten Sie die spezifischen Pufferinformationen im gedruckten Handbuch.
Activity
Gemessen an seiner Fähigkeit, die rekombinante humane BMP4-induzierte alkalische Phosphataseproduktion durch MC3T3-E1-Zellen zu hemmen. Die ED50 für diesen Effekt beträgt typischerweise 0,05-0,3 μg/mL in Gegenwart von 50 ng/mL rekombinantem humanem BMP4.
Endotoxin level
< 1,0 EU pro μg des Proteins, bestimmt mittels LAL-Methode.
Sequence
Met1-Cys232
Technical note
Bitte beachten Sie das gedruckte Handbuch für detaillierte Informationen.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioaktivitätBindungZellbasiertIn vivoELISA-Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PKSH031720_100µg
Gene symbol
Noggin/NOG
Gene ID
9241
UniProt accession
NP_005441.1
Storage, stability & shipping
Shelf life
12 Monate
Shipped at
Dieses Produkt wird als lyophilisiertes Pulver geliefert, das mit Kühlakkus versandt wird.
Short-term storage
Im Allgemeinen sind lyophilisierte Proteine bis zu 12 Monate lang bei -20 bis -80 °C stabil. Rekonstituierte Proteinlösungen können 2-7 Tage lang bei 4-8 °C gelagert werden. Aliquots von rekonstituierten Proben sind bei < -20 °C 3 Monate lang stabil.
Long-term storage
Im Allgemeinen sind lyophilisierte Proteine bei einer Lagerung von -20 bis -80 ℃ bis zu 12 Monate stabil. Rekonstituierte Proteinlösungen können 2-7 Tage bei 4-8 ℃ gelagert werden. Aliquots von rekonstituierten Proben sind bei < -20 ℃ 3 Monate stabil.
Aliquoting guidance
Das gesamte Fläschchen sofort rekonstituieren. Arbeitslösung aliquotieren; wiederholtes Einfrieren und Auftauen vermeiden.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Elabscience
£432.00£345.60