ABMIUM target intelligence
interleukin 18
IL18 identifies interleukin 18 in Homo sapiens (Human). This target record connects NCBI Gene 3606, UniProtKB Q14116 and related ABMIUM catalogue products.
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Research context & evidence
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IL18 is a pro-inflammatory cytokine involved in epithelial barrier repair and Th1 and natural-killer-cell immune responses. Signalling through IL18R1 and IL18RAP activates NF-kB and promotes inflammatory mediator production.
IL18 is studied in innate and adaptive immune responses, epithelial barrier biology, pyroptosis-associated inflammation and cytokine-driven IFNG production.
Names used across publications, databases and supplier catalogues.
